SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8402ab3dc40082b7856fc02bef1b51a8135b5f925af1bdba268826d4aa75f6b3' 
  AND token = 'ztachW/MU86XPJLuQiWNHtThcznMA7uRfP19AIb7huo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}