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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fb20f241cc016eecf672a144dac53bc1203d711ffe2651cdc87c0946e498943' 
  AND token = '9k4pV4YR9f3yRl7MEcWjoRYaG/r6QKwTbS2yX1ii7/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}