SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf5ad77f34f87b668c73c43ca1fbbbfe21dfa934e5241be1c0bbf72235488a66' 
  AND token = '+xQXCE76wVdOpbtxbA9KOiTefYUXN/bulViIe/JjlGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}