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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59dfce3c30ff529e1c56b7c29021acb7fc8db8ee4d1e937c3e4c259affe367bb' 
  AND token = '+Sc0x1aZtrCr9OVFqVUv902twSjDrvH/Z153JjiCB14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}