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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8db533ec5bcec9f9e82f8a0d106c3bce462912e001cb01f7d222f980f0a3126d' 
  AND token = 'zSRY2gCEGxhiX3HE3hxfUWCJ6P4KtIlFaJhzUhOeoOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}