SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550c605baf652d9d176f589c3aedd2fea41ebe24878868e5d46a838a4afa4355' 
  AND token = '9ZUk7B9p1/eNd+08VAeRinVlUzA8iqud6Q70zXl2fzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}