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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1554dd76af995556a2741d6a0cd8e5a1e1eb3a29c3afc56b6178bfe1277db171' 
  AND token = 'gMDlVmrhh+yzP/m9Ag4leeycfNsbQFFeorWriL4wNno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}