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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74bd8fdeda31be79508747fb3ce13ed0880feab3d794918be7790b02c549a848' 
  AND token = 'WD3l+vrN256Q02E6yx5aqOii/1fKr2+mA39F2b8Kw7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}