SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89423878e0cfd9d89a9bb74e8847da30709198ed68027780100422b7f2e3b206' 
  AND token = 'xN2YzkYMhLSXAV+U77qIs1F8IoEm7AWJ8hf/SoG10Aw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}