SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2acc6c5d5d51f51c25a96183735fb54de92db6fbd57c48b4d535b111e80f503d' 
  AND token = 'xvaJEw2UkoQXMgDNibbrct8fFT2LD3P7NX0YcpSboSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}