SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e20091878c92446fede0581ec8f124e10ad7dc42c18553fb6f8c64fe38d4e346' 
  AND token = 'zQwdSI0HtzwVig3oe0zQT0ZZZRXgNrMOzWdcTUpVKCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}