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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df27395033a85abf5ffca4dc847a24a3ec774432af1265f9ed5bf1e260f3614f' 
  AND token = '3+MQT/ovYXYR/ff0Usn5HG1IPp+fET3Hu6csMIFQZTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}