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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0518fd8effbcdc6dcecaae61cef4f8f94f6736650c85ac711cffa7bce33c6bfb' 
  AND token = 'CGAGq3QDk67XYEbPkbO7CFEa/3UQUcs8j0rsf7Jxsmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}