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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8ccdc6c223dacfb100c33a4c5f38f0b7a358357f7160131e02d74a548f4857a' 
  AND token = 'tUrqNJoUwzt7HEIk7PdMzYqrvY47Dh2/KBU/p8ExaUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}