SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e99342a779b35fad0f525a8a80de96695d4de267c924e46914c6bfeb631a4f43' 
  AND token = 'cPq/yehxn2BIvkm7fV5EDav3J+g8NVyiqCEUiOmBZbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}