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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ea0eb8217afe3646b8d561f0d42c2734deb42eceed0a5c77a7101c3860a305' 
  AND token = 'f0sMLmjKEvYDPoIutHVuXmTe/nETqXT59Cp42bzonpc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}