SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ac9df6c1dc084d70e03c32bd8068730ed28311ea2ab6718d2a164a8ada2a547' 
  AND token = 'FNHbu3aTcJ/Bzwx/M/M7MyiWdpwm6KE00c2sDKtbUWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}