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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f100a34e9a473ce87a15276014ac77fb17fd908adc2121e8cfbf23031dcdcb01' 
  AND token = 'ECSwxO44X3JCM4uJzCVydwgzZ3ob5iAz4y4WKAPujzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}