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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e577471d648816a79ef8d6e333d124e3c3ad8a06ebd2cb21ece4637e287ab802' 
  AND token = 'Eqa1zGiZ760PTgAk+G5uO6CBIRrHRshoatGHNIvR3gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}