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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be0805305a9487160c26a91e855544799d40c749a959bafe24264a50cc5b8228' 
  AND token = 'ArTKmag8tqry8os8zP4yiAkxLYBDCVBkb/Vwdmdp3SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}