SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9f6fdf4f89275f70d6dbe528c615eddc121a94c872a15dc85abed85edfa98d1' 
  AND token = '44nJOA6bv8Ag1IRLGikjPq9DXMqg8UNbAaivBXdruq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}