SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae6060fddeca5fe2b2fe78479442457bc7458a06c515596cd4e9e262bea80d36' 
  AND token = 'jNibXn7WaLVgwsBI/PutLtDPDDi7BGaBqBCaz/UQYe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}