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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b009381111c8ea16cdf8ffac6e8e000cb1b99d6a2f21325e7f0500a83b478d6' 
  AND token = 'WlyQ0W1pIpY/5sEYvkCHgO/o2msV8IP824TThY9gZog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}