SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d90469c45fb6434acd19122e0cf7d940a53c1a29fb0cca3082769a207c1b387' 
  AND token = 'UEIeM0au6rf+B9YYWe9uEaby9e44HBEoIyZRlRLDbC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}