SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd163c5ffb1434512717f0540b4837e4c894b42c09d14a7e314257e8ccb77553c' 
  AND token = 'aGvBSQ+cZgRdIXiTf9KjMSaoStP2FpP7JKjgPB22T/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}