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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '550f541dff489bcdc8fdc3d09ae7ea82a040b66ba2ddfe3f018f39e282b5ac14' 
  AND token = 'U0kX8H3XWShVSp+sH5Ask1nFPAVZ4SJPLJOa7pIt5Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}