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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbd4bb14627317f00b78221ef00b399818a4ebc70c561e1a54830dfb51daa24f' 
  AND token = 'UOPOY4XW7wT4q2fqR87QQ0BpQ5H0q2bvyQtM/nV9qrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}