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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '490d6f1fa9b66ed221c500a2a3cef36cb74fc0929e574819e2cb6eda4b6b9673' 
  AND token = '5gG/FHgR42VPNDCgxcbCtFboMtt9IoKd5fFjekOLud4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}