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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a8f6eb328810a6b50fb9aa10291529df54f4587d768f8afd8bf3788772b31c5' 
  AND token = 'wi6Xs5Lr96rTUJJ85rI/LohbiZCVnsZWpauLPPJpl5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}