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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '211d7049767f9be0eeaedd2002e26843a3f97cf827f60efcdf03cef7d4b6d629' 
  AND token = 'Gk9yrOvoGLNY+sIk7/y9gb+cNE7jTCMxtMt7BdQZquM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}