SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9ecafd5acf8b35d68c31e417378f43142a8be5077f165e7662b735b197965e0' 
  AND token = '0LjPir4UvLporfktLLzAXrTxlgg06aBQmepANyeyLow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}