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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a203a9b0fa0e6421fd6257a88d0e5e25e4dc1e18120896bf395d5c139428b232' 
  AND token = 'jGWdlBDyfEzxcANt0E+kYXTAW63xr61zlJmYhfdwwzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}