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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f1200122862994e980177a9eeff803d3fd1d3baa9e39fff28a18d81e95d859a' 
  AND token = 'Sk+1vG4TzVxP/YnPC3V8Z5yc528PwXU2TODiO+rla/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}