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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fd18955ef63fac5d08e766a38680a46293cfb24c8ebc9909575c8fb65e21c9e' 
  AND token = 'v1xCxk3FUvrs/EN5F/WiEYxHIafYvtfoIYwOqte6DdY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}