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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9acd9e7e60c4aa274799e3492ff64661f0a3f2bb2462a65d81c15d2394dcd4b4' 
  AND token = '6GP0bQIc3u7QrkRZFNbUadJUIq0BEjYl2bf4V0bhS/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}