SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dbf7d7ee20cd1f5d56988a07a57cec780393f9d90eaac76da36eb1f77c0e947' 
  AND token = '/oo6yyTBEcQ/FnROjaBA7+jX4iGw1RbeZ7/EeqFBONg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}