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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ac001084635bd9830ece003ff7d21123b4f949aeaccfd4a6139e5d5bcc098f' 
  AND token = '+ZYz1rNWBS60JRW5t8PeKWcK/5LXWmkDdzr+bGtQrBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}