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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '208ec0cf0fbcd958c18a90818b151057bc76930ea5ba3a0d5d779d23655f27cf' 
  AND token = 'YuEmyRZqwwM3zRK+UE24leAoxLsOXXOjTILQcDTGF2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}