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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52bafec71666ad2d35223905c74ee7c1eab22c4557c9576e1fa6ce121f8a5539' 
  AND token = '4Umg7dSYAUwaircjjbGaf8Pm+hsiohwXXwSjqc7uEZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}