SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '443deee7783320a470555907546201df778725a52f068dea11c2faffce7d0fa7' 
  AND token = 'vh6o+u+NvzfDhxTb/5es9vTI14dAVkcp3NQvtOp0UH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}