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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf82a13d1943c26af3c5a7e2f41ff4100510756e843e6cc78ceded0144b7dfa2' 
  AND token = 'Oxs3DNEF1MQg1LAopC4KQUhZ+aiKBUJtc26EK+eNfzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}