SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc5d13887e1496442110c769661d04bb90aedf43488e4e56ea6db63ba7a5a100' 
  AND token = 'y0qAkq+chR+yDmOn26qonZfU1xwoDS9Lg3m6aURAGow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}