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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1000404196871409378e339512c90ae749eef8dfb9b238cf41e94186d3032e02' 
  AND token = 'zQF02TUVm8vInmkb1a+iTjA2LK+qlG7Fia3wZb2oyTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}