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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee0502089d25f9b627b165aaa600c9d0c8331d124b3550f67b32d59c0d76459d' 
  AND token = 'ITvV+Feuzw5WwRsDCqpZrZoy9eplYWZkn7eIXYpRLR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}