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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76e42659cbf50e38c1e13eb8e6debc921944ce71527d1c7c57dcf098497b3f42' 
  AND token = 'zIdQQVZjHTGoTRUrCFQJ1zuPnIKi99y9td9LvwVv8o0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}