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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d9c1bf2da14f1af9e199958189c61d92b2b336140c1123cb4519a3d1df9bd9' 
  AND token = 'UIVOPqNVOT1oOdqAnGPGLCTwwk1RQ6Xx3xS9xi37T8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}