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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2381063982a9442911bc4855ed6fbdca6f6038c44a3fe3445c2a1d684284ee59' 
  AND token = 'K6RltHFC7bahouf9G3wLG0pWCrIYxvT25xtKVenLEFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}