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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6fc6b9a63c7504890fc4850c2132372c1f2270e3441c36a9326104927c883b3' 
  AND token = 'U38AeIHnD/wioWoBb7VSCXSEswczJyskdtUIi0uwzpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}