SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c0a52afd0e8adba9adc54af24fca97ad5f1b0fcd83fb5759a7bf8d2b173046' 
  AND token = 'xsu/u6/2vNGlMCW0WzhvAm+rw55bK5AjZaAHO74t9To=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}