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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2de3ea71f9d36e7f65aefa06943b12b3d8342e3abcfd695bf5af9314221ce10f' 
  AND token = '7Z9Yxb35cWHe6m2bTQbc9MMUOAOkWv9C6HoB8swKsAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}